Associated Papers
Familial Hyperkalemic Hypertension.
Cornelius RJ et al.
Comprehensive Physiology, 2024
Revisiting the NaCl cotransporter regulation by with-no-lysine kinases.
Bazúa-Valenti S et al.
American Journal of Physiology. Cell Physiology, 2015
A novel Ste20-related proline/alanine-rich kinase (SPAK)-independent pathway involving calcium-binding protein 39 (Cab39) and serine threonine kinase with no lysine member 4 (WNK4) in the activation of Na-K-Cl cotransporters.
Ponce-Coria J et al.
The Journal of Biological Chemistry, 2014
Kelch-like 3 and Cullin 3 regulate electrolyte homeostasis via ubiquitination and degradation of WNK4.
Shibata S et al.
Proceedings of the National Academy of Sciences of the United States of America, 2013
The WNKs: atypical protein kinases with pleiotropic actions.
McCormick JA et al.
Physiological Reviews, 2011
Characterization of the kinase activity of a WNK4 protein complex.
Ahlstrom R et al.
American Journal of Physiology. Renal Physiology, 2009
WNK4 kinase is a negative regulator of K+-Cl- cotransporters.
Garzón-Muvdi T et al.
American Journal of Physiology. Renal Physiology, 2007
Intersectin links WNK kinases to endocytosis of ROMK1.
He G et al.
The Journal of Clinical Investigation, 2007
WNK kinases influence TRPV4 channel function and localization.
Fu Y et al.
American Journal of Physiology. Renal Physiology, 2006
WNK kinases and the control of blood pressure.
Cope G et al.
Pharmacology & Therapeutics, 2005
Role of WNK kinases in regulating tubular salt and potassium transport and in the development of hypertension.
Gamba G
American Journal of Physiology. Renal Physiology, 2005
WNK4 regulates the balance between renal NaCl reabsorption and K+ secretion.
Kahle KT et al.
Nature Genetics, 2003
WNK kinases regulate thiazide-sensitive Na-Cl cotransport.
Yang CL et al.
The Journal of Clinical Investigation, 2003