Varaico: Literature-Extracted Genetic Variants

ADAM10

266 papers

RefSeq Summary

Members of the ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. This gene encodes and ADAM family member that cleaves many protein...

Pfam Domains

Reprolysin_2aa 239–446UCSCMetallo-peptidase family M12B Reprolysin-like

Disintegrinaa 466–546UCSCDisintegrin

ADAM10_Cys-richaa 591–646UCSCADAM10, cysteine-rich domain

Gene Aliases

HGNC Name

ADAM metallopeptidase domain 10

HGNC Alias Symbols

kuz; MADM; HsT18717; CD156C

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001110.4

p.P169R

c.506C>G

Surrounding Variants

1 paper

NM_001110.4

p.Q170E

c.508C>G

2 papers

NM_001110.4

p.G168D

c.503G>A

42 papers

NM_001110.4

p.Q170H

c.510G>T

42 papers

NM_001110.4

p.Q170H

c.510G>C

2 papers

NM_001110.4

p.G168S

c.502G>A

3 papers

NM_001110.4

p.Y167*

c.501C>G

3 papers

NM_001110.4

p.Y167*

c.501C>A

1 paper

NM_001110.4

p.Y167C

c.500A>G

1 paper

NM_001110.4

p.G172S

c.514G>A

1 paper

NM_001110.4

p.G172V

c.515G>T

1 paper

NM_001110.4

p.G172delFs

c.515delC

1 paper

NM_001110.4

p.C173Y

c.518G>A