Varaico: Literature-Extracted Genetic Variants

ADAMTS10

170 papers

RefSeq Summary

This gene belongs to the ADAMTS (a disintegrin and metalloproteinase domain with thrombospondin type-1 motifs) family of zinc-dependent proteases. ADAMTS proteases are complex secreted enzymes contain...

Pfam Domains

Pep_M12B_propepaa 40–129UCSCReprolysin family propeptide

Reprolysinaa 239–457UCSCReprolysin (M12B) family zinc metalloprotease

ADAMTS_CR_2aa 469–537UCSCADAMTS cysteine-rich domain 2

TSP_1aa 551–601UCSCThrombospondin type 1 domain

ADAMTS_CR_3aa 604–705UCSCADAMTS cysteine-rich domain

ADAMTS_spacer1aa 707–818UCSCADAM-TS Spacer 1

Gene Aliases

HGNC Name

ADAM metallopeptidase with thrombospondin type 1 motif 10

HGNC Alias Symbol

ADAM-TS10

Papers

RefSeq ID

Protein change

DNA change

1–12 of 173 variants

18 papers

NM_030957.4

p.G661R

c.1981G>C

18 papers

NM_030957.4

p.G661R

c.1981G>A

12 papers

NM_030957.4

p.A25T

c.73G>A

9 papers

NM_030957.4

p.R62Q

c.185G>A

9 papers

NM_030957.4

p.R237*

c.709C>T

6 papers

NM_030957.4

p.A387T

c.1159G>A

5 papers

NM_030957.4

p.H1101Q

c.3303T>G

5 papers

NM_030957.4

p.H1101Q

c.3303T>A

3 papers

NM_030957.4

p.L14Q

c.41T>A

3 papers

NM_030957.4

p.S134T

c.401G>C

3 papers

NM_030957.4

p.E153K

c.457G>A

3 papers

NM_030957.4

p.R239H

c.716G>A