Varaico: Literature-Extracted Genetic Variants

ADAMTS10

170 papers

RefSeq Summary

This gene belongs to the ADAMTS (a disintegrin and metalloproteinase domain with thrombospondin type-1 motifs) family of zinc-dependent proteases. ADAMTS proteases are complex secreted enzymes contain...

Pfam Domains

Pep_M12B_propepaa 40–129UCSCReprolysin family propeptide

Reprolysinaa 239–457UCSCReprolysin (M12B) family zinc metalloprotease

ADAMTS_CR_2aa 469–537UCSCADAMTS cysteine-rich domain 2

TSP_1aa 551–601UCSCThrombospondin type 1 domain

ADAMTS_CR_3aa 604–705UCSCADAMTS cysteine-rich domain

ADAMTS_spacer1aa 707–818UCSCADAM-TS Spacer 1

Gene Aliases

HGNC Name

ADAM metallopeptidase with thrombospondin type 1 motif 10

HGNC Alias Symbol

ADAM-TS10

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_030957.4

p.S640L

c.1919C>T

Surrounding Variants

1 paper

NM_030957.4

p.T642T

c.1926G>A

1 paper

NM_030957.4

p.E646K

c.1936G>A

1 paper

NM_030957.4

p.T652T

c.1956G>A

18 papers

NM_030957.4

p.G661R

c.1981G>C

18 papers

NM_030957.4

p.G661R

c.1981G>A

1 paper

NM_030957.4

p.P663T

c.1987C>A

1 paper

NM_030957.4

p.V669delFs

c.2005delC

1 paper

NM_030957.4

p.V669fs

c.2005_2006fs

1 paper

NM_030957.4

p.C672C

c.2016C>T

1 paper

NM_030957.4

p.S674_G675del2

c.2020_2024del6

1 paper

NM_030957.4

p.R684*

c.2050C>T

1 paper

NM_030957.4

p.D689N

c.2065G>A