Varaico: Literature-Extracted Genetic Variants

AKT1

3,188 papers

RefSeq Summary

This gene encodes one of the three members of the human AKT serine-threonine protein kinase family which are often referred to as protein kinase B alpha, beta, and gamma. These highly similar AKT prot...

Pfam Domains

PHaa 6–108UCSCPH domain

Pkinaseaa 150–408UCSCProtein kinase domain

Pkinase_Caa 429–474UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 1

HGNC Alias Symbols

PKB; PRKBA; RAC-alpha

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001382430.1

p.S463R

c.1389C>A

Surrounding Variants

1 paper

NM_001382430.1

p.S463R

c.1389C>G

6 papers

NM_001382430.1

p.E464K

c.1390G>A

2 papers

NM_001382430.1

p.S463R

c.1387A>C

8 papers

NM_001382430.1

p.R465C

c.1393C>T

2 papers

NM_001382430.1

p.R465G

c.1393C>G

1 paper

NM_001382430.1

p.D462V

c.1385A>T

1 paper

NM_001382430.1

p.D462G

c.1385A>G

1 paper

NM_001382430.1

p.R465L

c.1394G>T

1 paper

NM_001382430.1

p.D462H

c.1384G>C

8 papers

NM_001382430.1

p.R465H

c.1394G>A

1 paper

NM_001382430.1

p.V461V

c.1383G>T

1 paper

NM_001382430.1

p.R466W

c.1396A>T