Varaico: Literature-Extracted Genetic Variants

AKT1

3,188 papers

RefSeq Summary

This gene encodes one of the three members of the human AKT serine-threonine protein kinase family which are often referred to as protein kinase B alpha, beta, and gamma. These highly similar AKT prot...

Pfam Domains

PHaa 6–108UCSCPH domain

Pkinaseaa 150–408UCSCProtein kinase domain

Pkinase_Caa 429–474UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 1

HGNC Alias Symbols

PKB; PRKBA; RAC-alpha

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001382430.1

p.T308S

c.922A>T

Surrounding Variants

35 papers

NM_001382430.1

p.T308A

c.922A>G

1 paper

NM_001382430.1

p.T308P

c.922A>C

1 paper

NM_001382430.1

p.D302_K307del6

c.904_920del18

2 papers

NM_001382430.1

p.K307N

c.921G>T

2 papers

NM_001382430.1

p.K307N

c.921G>C

1 paper

NM_001382430.1

p.K307K

c.921G>A

2 papers

NM_001382430.1

p.T308S

c.923C>G

1 paper

NM_001382430.1

p.T308T

c.924C>A

1 paper

NM_001382430.1

p.T305_K307del3

c.913_920del9

1 paper

NM_001382430.1

p.G303_T308del6

c.907_923del18

1 paper

NM_001382430.1

p.K307E

c.919A>G

2 papers

NM_001382430.1

p.M306I

c.918G>T