Varaico: Literature-Extracted Genetic Variants

AKT1

3,188 papers

RefSeq Summary

This gene encodes one of the three members of the human AKT serine-threonine protein kinase family which are often referred to as protein kinase B alpha, beta, and gamma. These highly similar AKT prot...

Pfam Domains

PHaa 6–108UCSCPH domain

Pkinaseaa 150–408UCSCProtein kinase domain

Pkinase_Caa 429–474UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 1

HGNC Alias Symbols

PKB; PRKBA; RAC-alpha

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

49 papers

NM_001382430.1

p.K179M

c.536A>T

Surrounding Variants

3 papers

NM_001382430.1

p.K179R

c.536A>G

1 paper

NM_001382430.1

p.I180F

c.538A>T

1 paper

NM_001382430.1

p.I180T

c.539T>C

1 paper

NM_001382430.1

p.M178T

c.533T>C

1 paper

NM_001382430.1

p.I180N

c.539T>A

2 papers

NM_001382430.1

p.M178V

c.532A>G

1 paper

NM_001382430.1

p.L181F

c.541C>T

1 paper

NM_001382430.1

p.L181V

c.541C>G

1 paper

NM_001382430.1

p.A177G

c.530C>G

1 paper

NM_001382430.1

p.A177S

c.529G>T

1 paper

NM_001382430.1

p.Y176_A177insFs

c.528_529insCT

1 paper

NM_001382430.1

p.A177P

c.529G>C