Varaico: Literature-Extracted Genetic Variants

AKT1

3,188 papers

RefSeq Summary

This gene encodes one of the three members of the human AKT serine-threonine protein kinase family which are often referred to as protein kinase B alpha, beta, and gamma. These highly similar AKT prot...

Pfam Domains

PHaa 6–108UCSCPH domain

Pkinaseaa 150–408UCSCProtein kinase domain

Pkinase_Caa 429–474UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 1

HGNC Alias Symbols

PKB; PRKBA; RAC-alpha

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_001382430.1

p.N54I

c.161A>T

Surrounding Variants

1 paper

NM_001382430.1

p.N54T

c.161A>C

3 papers

NM_001382430.1

p.N54K

c.162C>G

2 papers

NM_001382430.1

p.N54K

c.162C>A

2 papers

NM_001382430.1

p.F55L

c.163T>C

1 paper

NM_001382430.1

p.N53_N54del2

c.157_161del6

1 paper

NM_001382430.1

p.F55S

c.164T>C

6 papers

NM_001382430.1

p.F55Y

c.164T>A

1 paper

NM_001382430.1

p.F55F

c.165C>T

2 papers

NM_001382430.1

p.F55L

c.165C>G

2 papers

NM_001382430.1

p.F55L

c.165C>A

2 papers

NM_001382430.1

p.N53Y

c.157A>T

3 papers

NM_001382430.1

p.N53H

c.157A>C