Varaico: Literature-Extracted Genetic Variants

AKT1

3,188 papers

RefSeq Summary

This gene encodes one of the three members of the human AKT serine-threonine protein kinase family which are often referred to as protein kinase B alpha, beta, and gamma. These highly similar AKT prot...

Pfam Domains

PHaa 6–108UCSCPH domain

Pkinaseaa 150–408UCSCProtein kinase domain

Pkinase_Caa 429–474UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 1

HGNC Alias Symbols

PKB; PRKBA; RAC-alpha

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001382430.1

p.E40E

c.120G>A

Surrounding Variants

6 papers

NM_001382430.1

p.R41W

c.121C>T

1 paper

NM_001382430.1

p.E40G

c.119A>G

2 papers

NM_001382430.1

p.E40A

c.119A>C

1 paper

NM_001382430.1

p.K39delFs

c.117delC

1 paper

NM_001382430.1

p.E40*

c.118G>T

33 papers

NM_001382430.1

p.E40K

c.118G>A

2 papers

NM_001382430.1

p.R41Q

c.122G>A

6 papers

NM_001382430.1

p.K39N

c.117G>T

1 paper

NM_001382430.1

p.R41R

c.123G>T

6 papers

NM_001382430.1

p.K39N

c.117G>C

1 paper

NM_001382430.1

p.K39K

c.117G>A

3 papers

NM_001382430.1

p.P42S

c.124C>T