Varaico: Literature-Extracted Genetic Variants

AKT3

598 papers

RefSeq Summary

The protein encoded by this gene is a member of the AKT, also called PKB, serine/threonine protein kinase family. AKT kinases are known to be regulators of cell signaling in response to insulin and g...

Pfam Domains

PHaa 6–107UCSCPH domain

Pkinaseaa 148–405UCSCProtein kinase domain

Pkinase_Caa 426–473UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 3

HGNC Alias Symbols

PKBG; RAC-gamma; PRKBG

Papers

RefSeq ID

Protein change

DNA change

1–12 of 575 variants

103 papers

NM_005465.7

p.E17K

c.49G>A

30 papers

NM_005465.7

p.R465W

c.1393C>T

15 papers

NM_005465.7

p.N229S

c.686A>G

14 papers

NM_005465.7

p.E40K

c.118G>A

14 papers

NM_005465.7

p.G171R

c.511G>C

14 papers

NM_005465.7

p.G171R

c.511G>A

14 papers

NM_005465.7

p.V183D

c.548T>A

10 papers

NM_005465.7

p.D322N

c.964G>A

9 papers

NM_005465.7

p.Q78K

c.232C>A

8 papers

NM_005465.7

p.R166*

c.496C>T

7 papers

NM_005465.7

p.N53K

c.159C>A

7 papers

NM_005465.7

p.W79C

c.237G>T