Varaico: Literature-Extracted Genetic Variants

AKT3

598 papers

RefSeq Summary

The protein encoded by this gene is a member of the AKT, also called PKB, serine/threonine protein kinase family. AKT kinases are known to be regulators of cell signaling in response to insulin and g...

Pfam Domains

PHaa 6–107UCSCPH domain

Pkinaseaa 148–405UCSCProtein kinase domain

Pkinase_Caa 426–473UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 3

HGNC Alias Symbols

PKBG; RAC-gamma; PRKBG

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

8 papers

NM_005465.7

p.R166*

c.496C>T

Surrounding Variants

1 paper

NM_005465.7

p.R166Q

c.497G>A

1 paper

NM_005465.7

p.E167Q

c.499G>C

1 paper

NM_005465.7

p.E167D

c.501G>T

1 paper

NM_005465.7

p.E167D

c.501G>C

2 papers

NM_005465.7

p.K168R

c.503A>G

1 paper

NM_005465.7

p.V162A

c.485T>C

1 paper

NM_005465.7

p.V162fs

c.484_485fs

1 paper

NM_005465.7

p.V162I

c.484G>A

1 paper

NM_005465.7

p.G171*

c.511G>T

14 papers

NM_005465.7

p.G171R

c.511G>C

14 papers

NM_005465.7

p.G171R

c.511G>A

1 paper

NM_005465.7

p.K161E

c.481A>G