Varaico: Literature-Extracted Genetic Variants

Gene:APOE
Variant:p.K161N

APOE

2,396 papers

RefSeq Summary

The protein encoded by this gene is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich li...

Pfam Domains

Apolipoproteinaa 81–288UCSCApolipoprotein A1/A4/E domain
Apolipoproteinaa 81–288UCSCApolipoprotein A1/A4/E domain

Gene Aliases

HGNC Name

apolipoprotein E

HGNC Previous Symbol

AD2

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
4 papers
NM_000041.4
p.K161N
c.483G>T
Surrounding Variants
4 papers
NM_000041.4
p.K161N
c.483G>C
1 paper
NM_000041.4
p.K161R
c.482A>G
5 papers
NM_000041.4
p.L162V
c.484C>G
1 paper
NM_000041.4
p.R160R
c.480C>T
1 paper
NM_000041.4
p.K161_R163del3
c.481_488del9
1 paper
NM_000041.4
p.K161_R165del5
c.481_494del15
1 paper
NM_000041.4
p.L162L
c.486G>T
1 paper
NM_000041.4
p.R163del1
c.487_488delCGT
33 papers
NM_000041.4
p.R163C
c.487C>T
1 paper
NM_000041.4
p.R160H
c.479G>A
7 papers
NM_000041.4
p.R160L
c.479G>T
2 papers
NM_000041.4
p.R160S
c.478C>A
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."