Varaico: Literature-Extracted Genetic Variants

Gene:AURKA
Variant:p.D274N

AURKA

577 papers

RefSeq Summary

The protein encoded by this gene is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. The encod...

Pfam Domains

Pkinaseaa 133–383UCSCProtein kinase domain

Gene Aliases

HGNC Name

aurora kinase A

HGNC Previous Symbols

STK15; STK6

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
10 papers
NM_198437.3
p.D274N
c.820G>A
Surrounding Variants
3 papers
NM_198437.3
p.D274A
c.821A>C
1 paper
NM_198437.3
p.S278A
c.832T>G
1 paper
NM_198437.3
p.S278L
c.833C>T
1 paper
NM_198437.3
p.G268E
c.803G>A
1 paper
NM_198437.3
p.G268R
c.802G>C
1 paper
NM_198437.3
p.G268R
c.802G>A
1 paper
NM_198437.3
p.G265E
c.794G>A
2 papers
NM_198437.3
p.P282P
c.846A>G
1 paper
NM_198437.3
p.S283A
c.847T>G
1 paper
NM_198437.3
p.S283T
c.847T>A
1 paper
NM_198437.3
p.G265R
c.793G>C
1 paper
NM_198437.3
p.G265R
c.793G>A
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