Varaico: Literature-Extracted Genetic Variants

BRAF

18,221 papers

RefSeq Summary

This gene encodes a protein belonging to the RAF family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERK signaling pathway, which affects cell division, ...

Pfam Domains

RBDaa 156–227UCSCRaf-like Ras-binding domain

C1_1aa 235–282UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

PK_Tyr_Ser-Thraa 497–754UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

B-Raf proto-oncogene, serine/threonine kinase

HGNC Alias Symbols

BRAF1; BRAF-1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_004333.6

p.K601delins

c.1802delinsAGAT

Surrounding Variants

205 papers

NM_004333.6

p.K601N

c.1803A>T

3 papers

NM_004333.6

p.K601K

c.1803A>G

205 papers

NM_004333.6

p.K601N

c.1803A>C

1 paper

NM_004333.6

p.K601fs

c.1801_1802fs

2 papers

NM_004333.6

p.A598_K601ins1

c.1794_1802dup9

3 papers

NM_004333.6

p.V600_K601delins

c.1799_1803delinsAT

1 paper

NM_004333.6

p.V600_K601delins

c.1799_1803delinsAC

1 paper

NM_004333.6

p.V600_K601delFs

c.1799_1802del4

1 paper

NM_004333.6

p.T599_K601delins

c.1797_1803delinsTGAGAAT

5 papers

NM_004333.6

p.S602A

c.1804T>G

3 papers

NM_004333.6

p.S602P

c.1804T>C

6 papers

NM_004333.6

p.S602T

c.1804T>A