Varaico: Literature-Extracted Genetic Variants

BRAF

18,221 papers

RefSeq Summary

This gene encodes a protein belonging to the RAF family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERK signaling pathway, which affects cell division, ...

Pfam Domains

RBDaa 156–227UCSCRaf-like Ras-binding domain

C1_1aa 235–282UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

PK_Tyr_Ser-Thraa 497–754UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

B-Raf proto-oncogene, serine/threonine kinase

HGNC Alias Symbols

BRAF1; BRAF-1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_004333.6

p.T599ins1

c.1795_1796insCTA

Surrounding Variants

6 papers

NM_004333.6

p.T599S

c.1795A>T

14 papers

NM_004333.6

p.T599A

c.1795A>G

2 papers

NM_004333.6

p.T599P

c.1795A>C

2 papers

NM_004333.6

p.T599ins1

c.1795_1796insGTT

3 papers

NM_004333.6

p.T599_V600ins2

c.1795_1799ins6

1 paper

NM_004333.6

p.T599_V600insAGA

c.1795_1799ins9

3 papers

NM_004333.6

p.T599ins9

c.1795_1796ins27

4 papers

NM_004333.6

p.T599ins1

c.1795_1796insTAA

1 paper

NM_004333.6

p.T599fs

c.1795_1796fs

14 papers

NM_004333.6

p.A598_T599ins1

c.1794_1795insGTT

1 paper

NM_004333.6

p.I582_A598ins5

c.1746_1793dup48

1 paper

NM_004333.6

p.A598_T599ins1

c.1794_1795insACA