Varaico: Literature-Extracted Genetic Variants

BRAF

18,221 papers

RefSeq Summary

This gene encodes a protein belonging to the RAF family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERK signaling pathway, which affects cell division, ...

Pfam Domains

RBDaa 156–227UCSCRaf-like Ras-binding domain

C1_1aa 235–282UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

PK_Tyr_Ser-Thraa 497–754UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

B-Raf proto-oncogene, serine/threonine kinase

HGNC Alias Symbols

BRAF1; BRAF-1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_004333.6

p.A12delins

c.34_35delinsAA

Surrounding Variants

2 papers

NM_004333.6

p.A12V

c.35C>T

3 papers

NM_004333.6

p.A12G

c.35C>G

1 paper

NM_004333.6

p.A12insFs

c.34dupG

1 paper

NM_004333.6

p.A12ins2

c.35_36ins6

2 papers

NM_004333.6

p.A12delins

c.35_36delinsAG

1 paper

NM_004333.6

p.A12delins

c.34_35delinsTT

1 paper

NM_004333.6

p.A12delins

c.34_35delinsAT

2 papers

NM_004333.6

p.G11_A12del1

c.32_34delCGC

1 paper

NM_004333.6

p.G9_A12delFs

c.27_34del8

1 paper

NM_004333.6

p.G9_A12del0

c.26_34del9

51 papers

NM_004333.6

p.A12S

c.34G>T

1 paper

NM_004333.6

p.A12A

c.36G>T