Varaico: Literature-Extracted Genetic Variants

Gene:CASP3
Variant:p.L33R

CASP3

926 papers

RefSeq Summary

The protein encoded by this gene is a cysteine-aspartic acid protease that plays a central role in the execution-phase of cell apoptosis. The encoded protein cleaves and inactivates poly(ADP-ribose) p...

Pfam Domains

Peptidase_C14aa 44–274UCSCCaspase domain

Gene Aliases

HGNC Name

caspase 3

HGNC Alias Symbols

CPP32; CPP32B; Yama; apopain

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
16 papers
NM_004346.4
p.L33R
c.98T>G
Surrounding Variants
1 paper
NM_004346.4
p.L33Q
c.98T>A
1 paper
NM_004346.4
p.L33Fs
c.97_98delinsCFs
1 paper
NM_004346.4
p.L33V
c.97C>G
1 paper
NM_004346.4
p.D34H
c.100G>C
1 paper
NM_004346.4
p.G30_S32delFs
c.88_94del7
1 paper
NM_004346.4
p.D34A
c.101A>C
1 paper
NM_004346.4
p.S32T
c.94T>A
1 paper
NM_004346.4
p.D34D
c.102C>T
2 papers
NM_004346.4
p.I31M
c.93A>G
1 paper
NM_004346.4
p.I31T
c.92T>C
1 paper
NM_004346.4
p.G30delFs
c.90delT
1 paper
NM_004346.4
p.G30delFs
c.89_90delTC
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."