Varaico: Literature-Extracted Genetic Variants

Gene:CASP3
Variant:p.E25K

CASP3

926 papers

RefSeq Summary

The protein encoded by this gene is a cysteine-aspartic acid protease that plays a central role in the execution-phase of cell apoptosis. The encoded protein cleaves and inactivates poly(ADP-ribose) p...

Pfam Domains

Peptidase_C14aa 44–274UCSCCaspase domain

Gene Aliases

HGNC Name

caspase 3

HGNC Alias Symbols

CPP32; CPP32B; Yama; apopain

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_004346.4
p.E25K
c.73G>A
Surrounding Variants
1 paper
NM_004346.4
p.S26T
c.76T>A
1 paper
NM_004346.4
p.S24C
c.70A>T
1 paper
NM_004346.4
p.G23E
c.68G>A
1 paper
NM_004346.4
p.G23*
c.67G>T
1 paper
NM_004346.4
p.M27V
c.79A>G
2 papers
NM_004346.4
p.H22Q
c.66T>A
3 papers
NM_004346.4
p.H22R
c.65A>G
1 paper
NM_004346.4
p.H22Y
c.64C>T
6 papers
NM_004346.4
p.D28A
c.83A>C
1 paper
NM_004346.4
p.D28fs
c.82_83fs
1 paper
NM_004346.4
p.S29P
c.85T>C
1 paper
NM_004346.4
p.I21L
c.61A>C
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."