Varaico: Literature-Extracted Genetic Variants

Gene:CDC25C
Variant:p.K240E

CDC25C

175 papers

RefSeq Summary

This gene encodes a conserved protein that plays a key role in the regulation of cell division. The encoded protein directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It...

Pfam Domains

M-inducer_phospaa 190–271UCSCM-phase inducer phosphatase
Rhodaneseaa 307–421UCSCRhodanese-like domain

Gene Aliases

HGNC Name

cell division cycle 25C

HGNC Previous Symbol

CDC25

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_001790.5
p.K240E
c.718A>G
Surrounding Variants
1 paper
NM_001790.5
p.V241A
c.722T>C
1 paper
NM_001790.5
p.T236T
c.708A>T
1 paper
NM_001790.5
p.K244*
c.730A>T
1 paper
NM_001790.5
p.K244fs
c.730_731fs
2 papers
NM_001790.5
p.K244delFs
c.731delT
2 papers
NM_001790.5
p.D234G
c.701A>G
1 paper
NM_001790.5
p.K233E
c.697A>G
7 papers
NM_001790.5
p.S216A
c.646T>G
1 paper
NM_001790.5
p.S214A
c.640T>G
1 paper
NM_001790.5
p.R213C
c.637C>T
1 paper
NM_001790.5
p.T261I
c.782C>T
1 paper
NM_001790.5
p.S263A
c.787T>G
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