Varaico: Literature-Extracted Genetic Variants

Gene:COMT
Variant:p.A102T

COMT

2,857 papers

RefSeq Summary

Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-met...

Pfam Domains

Methyltransf_3aa 67–228UCSCO-methyltransferase

Gene Aliases

HGNC Name

catechol-O-methyltransferase

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
7 papers
NM_000754.4
p.A102T
c.304G>A
Surrounding Variants
3 papers
NM_000754.4
p.D101G
c.302A>G
NM_007310.3
p.D51G
c.152A>G
1 paper
NM_000754.4
p.V103A
c.308T>C
1 paper
NM_000754.4
p.V100L
c.298G>C
1 paper
NM_000754.4
p.V100L
c.298G>T
1 paper
NM_000754.4
p.Q105R
c.314A>G
1 paper
NM_000754.4
p.K98K
c.294G>A
7 papers
NM_000754.4
p.Q108Q
c.324G>A
3 papers
NM_000754.4
p.S110F
c.329C>T
NM_007310.3
p.S60F
c.179C>T
1 paper
NM_000754.4
p.S110S
c.330C>T
1 paper
NM_000754.4
p.V111M
c.331G>A
1 paper
NM_000754.4
p.L115P
c.344T>C
1 paper
NM_000754.4
p.A117T
c.349G>A
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