Varaico: Literature-Extracted Genetic Variants

CRBN

173 papers

RefSeq Summary

This gene encodes a protein related to the Lon protease protein family. In rodents and other mammals this gene product is found in the cytoplasm localized with a calcium channel membrane protein, and ...

Pfam Domains

LON_substr_bdgaa 80–317UCSCATP-dependent protease La (LON) substrate-binding domain

Yippee-Mis18aa 319–437UCSCYippee zinc-binding/DNA-binding /Mis18, centromere assembly

Gene Aliases

HGNC Name

cereblon

HGNC Previous Symbol

MRT2A

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_016302.4

p.N236T

c.707A>C

Surrounding Variants

1 paper

NM_016302.4

p.T238N

c.713C>A

1 paper

NM_016302.4

p.P241fs

c.721_722fs

1 paper

NM_016302.4

p.P241fs

c.721_722fs

1 paper

NM_016302.4

p.R242G

c.724C>G

1 paper

NM_016302.4

p.Y245Y

c.735T>C

4 papers

NM_016302.4

p.D249Y

c.745G>T

1 paper

NM_016302.4

p.D249N

c.745G>A

1 paper

NM_016302.4

p.A250T

c.748G>A

1 paper

NM_016302.4

p.M254V

c.760A>G

1 paper

NM_016302.4

p.R262R

c.786T>C

1 paper

NM_016302.4

p.E266*

c.796G>T

1 paper

NM_016302.4

p.N267S

c.800A>G