Varaico: Literature-Extracted Genetic Variants

CXCR4

764 papers

RefSeq Summary

This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to suppo...

Pfam Domains

CXCR4_Naa 6–38UCSCCXCR4 Chemokine receptor N terminal

7tm_1aa 55–302UCSC7 transmembrane receptor (rhodopsin family)

Gene Aliases

HGNC Name

C-X-C motif chemokine receptor 4

HGNC Alias Symbols

LESTR; NPY3R; HM89; NPYY3R; D2S201E; fusin; HSY3RR; NPYR; CD184

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003467.3

p.S339A

c.1015T>G

Surrounding Variants

9 papers

NM_003467.3

p.S339fs

c.1015_1016fs

1 paper

NM_003467.3

p.S338delFs

c.1014delT

3 papers

NM_003467.3

p.S339F

c.1016C>T

1 paper

NM_003467.3

p.S339C

c.1016C>G

2 papers

NM_003467.3

p.S339insFs

c.1016_1017insT

1 paper

NM_003467.3

p.S338_S339insFs

c.1012_1015dup4

1 paper

NM_003467.3

p.S339Y

c.1016C>A

4 papers

NM_003467.3

p.S338_S339delFs

c.1012_1015del4

2 papers

NM_003467.3

p.S338insFs

c.1013dupC

12 papers

NM_003467.3

p.S338fs

c.1012_1013fs

1 paper

NM_003467.3

p.G336_S338delFs

c.1007_1013del7

2 papers

NM_003467.3

p.S339insFs

c.1016_1017insC