Varaico: Literature-Extracted Genetic Variants

CXCR4

764 papers

RefSeq Summary

This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to suppo...

Pfam Domains

CXCR4_Naa 6–38UCSCCXCR4 Chemokine receptor N terminal

7tm_1aa 55–302UCSC7 transmembrane receptor (rhodopsin family)

Gene Aliases

HGNC Name

C-X-C motif chemokine receptor 4

HGNC Alias Symbols

LESTR; NPY3R; HM89; NPYY3R; D2S201E; fusin; HSY3RR; NPYR; CD184

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_003467.3

p.D262E

c.786C>G

Surrounding Variants

2 papers

NM_003467.3

p.D262E

c.786C>A

6 papers

NM_003467.3

p.D262A

c.785A>C

4 papers

NM_003467.3

p.D262N

c.784G>A

2 papers

NM_003467.3

p.S263F

c.788C>T

1 paper

NM_003467.3

p.S263Y

c.788C>A

3 papers

NM_003467.3

p.I261I

c.783C>T

1 paper

NM_003467.3

p.S260N

c.779G>A

1 paper

NM_003467.3

p.S260delFs

c.778delT

1 paper

NM_003467.3

p.I265V

c.793A>G

1 paper

NM_003467.3

p.I265T

c.794T>C

1 paper

NM_003467.3

p.L266delFs

c.796_797delAG

27 papers

NM_003467.3

p.L267L

c.801G>A