Varaico: Literature-Extracted Genetic Variants

DDR2

688 papers

RefSeq Summary

This gene encodes a member of the discoidin domain receptor subclass of the receptor tyrosine kinase (RTKs) protein family. RTKs play a key role in the communication of cells with their microenvironme...

Pfam Domains

F5_F8_type_Caa 45–182UCSCF5/8 type C domain

DDR1-2_DS-likeaa 190–366UCSCDiscoidin domain-containing receptor 1/2, DS-like domain

PK_Tyr_Ser-Thraa 563–849UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

discoidin domain receptor tyrosine kinase 2

HGNC Previous Symbols

TYRO10; NTRKR3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006182.4

p.L239L

c.717G>T

Surrounding Variants

2 papers

NM_006182.4

p.L239P

c.716T>C

14 papers

NM_006182.4

p.L239R

c.716T>G

1 paper

NM_006182.4

p.L239M

c.715C>A

1 paper

NM_006182.4

p.G238D

c.713G>A

1 paper

NM_006182.4

p.D241N

c.721G>A

1 paper

NM_006182.4

p.S237F

c.710C>T

1 paper

NM_006182.4

p.F242S

c.725T>C

1 paper

NM_006182.4

p.T243S

c.727A>T

1 paper

NM_006182.4

p.T243fs

c.727_728fs

1 paper

NM_006182.4

p.T243S

c.728C>G

1 paper

NM_006182.4

p.V236M

c.706G>A

1 paper

NM_006182.4

p.T243T

c.729C>A