Varaico: Literature-Extracted Genetic Variants

DDR2

688 papers

RefSeq Summary

This gene encodes a member of the discoidin domain receptor subclass of the receptor tyrosine kinase (RTKs) protein family. RTKs play a key role in the communication of cells with their microenvironme...

Pfam Domains

F5_F8_type_Caa 45–182UCSCF5/8 type C domain

DDR1-2_DS-likeaa 190–366UCSCDiscoidin domain-containing receptor 1/2, DS-like domain

PK_Tyr_Ser-Thraa 563–849UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

discoidin domain receptor tyrosine kinase 2

HGNC Previous Symbols

TYRO10; NTRKR3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006182.4

p.D728delFs

c.2184delC

Surrounding Variants

8 papers

NM_006182.4

p.I726R

c.2177T>G

3 papers

NM_006182.4

p.I724M

c.2172C>G

2 papers

NM_006182.4

p.L735M

c.2203C>A

1 paper

NM_006182.4

p.K720T

c.2159A>C

2 papers

NM_006182.4

p.Y736F

c.2207A>T

5 papers

NM_006182.4

p.G719A

c.2156G>C

3 papers

NM_006182.4

p.G719S

c.2155G>A

5 papers

NM_006182.4

p.G719C

c.2155G>T

1 paper

NM_006182.4

p.V718M

c.2152G>A

6 papers

NM_006182.4

p.Y740C

c.2219A>G

4 papers

NM_006182.4

p.Y740F

c.2219A>T

1 paper

NM_006182.4

p.C716Y

c.2147G>A