Varaico: Literature-Extracted Genetic Variants

Gene:DHFR
Variant:p.P26Q

DHFR

423 papers

RefSeq Summary

Dihydrofolate reductase converts dihydrofolate into tetrahydrofolate, a methyl group shuttle required for the de novo synthesis of purines, thymidylic acid, and certain amino acids. While the function...

Pfam Domains

DHFR_1aa 4–126UCSCDihydrofolate reductase

Gene Aliases

HGNC Name

dihydrofolate reductase

HGNC Alias Symbol

DHFR1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
4 papers
NM_000791.4
p.P26Q
c.77C>A
Surrounding Variants
1 paper
NM_000791.4
p.P26L
c.77C>T
1 paper
NM_000791.4
p.W25C
c.75G>T
1 paper
NM_000791.4
p.P24_W25delFs
c.70_74del5
1 paper
NM_000791.4
p.P27S
c.79C>T
2 papers
NM_000791.4
p.N20_P26delFs
c.60_78del19
2 papers
NM_000791.4
p.W25R
c.73T>C
1 paper
NM_000791.4
p.W25R
c.73T>A
1 paper
NM_000791.4
p.I17_P24delFs
c.51_72del22
1 paper
NM_000791.4
p.P27P
c.81G>A
4 papers
NM_000791.4
p.L28F
c.82C>T
1 paper
NM_000791.4
p.L28V
c.82C>G
1 paper
NM_000791.4
p.P24fs
c.70_71fs
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."