Varaico: Literature-Extracted Genetic Variants

DICER1

1,122 papers

RefSeq Summary

This gene encodes a protein possessing an RNA helicase motif containing a DEXH box in its amino terminus and an RNA motif in the carboxy terminus. The encoded protein functions as a ribonuclease and i...

Pfam Domains

DEADaa 45–213UCSCDEAD/DEAH box helicase

Dicer_PBDaa 267–367UCSCDicer, partner-binding domain

Helicase_Caa 471–555UCSCHelicase conserved C-terminal domain

Dicer_dimeraa 630–719UCSCDicer dimerisation domain

Dicer_platformaa 761–887UCSCDicer, platform domain

PAZaa 894–1064UCSCPAZ domain

Gene Aliases

HGNC Name

dicer 1, ribonuclease III

HGNC Previous Symbol

MNG1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_177438.3

p.E1813delins

c.5437_5438delinsTC

Surrounding Variants

22 papers

NM_177438.3

p.E1813V

c.5438A>T

110 papers

NM_177438.3

p.E1813G

c.5438A>G

44 papers

NM_177438.3

p.E1813A

c.5438A>C

102 papers

NM_177438.3

p.E1813D

c.5439G>T

5 papers

NM_177438.3

p.E1813*

c.5437G>T

2 papers

NM_177438.3

p.F1812insFs

c.5436dupT

101 papers

NM_177438.3

p.E1813D

c.5439G>C

76 papers

NM_177438.3

p.E1813Q

c.5437G>C

94 papers

NM_177438.3

p.E1813K

c.5437G>A

5 papers

NM_177438.3

p.E1813E

c.5439G>A

2 papers

NM_177438.3

p.F1812S

c.5435T>C

19 papers

NM_177438.3

p.S1814L

c.5441C>T