Varaico: Literature-Extracted Genetic Variants

Gene:E2F1
Variant:p.K161R

E2F1

544 papers

RefSeq Summary

The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is...

Pfam Domains

WHD_E2F_TDPaa 128–192UCSCE2F/DP family winged-helix DNA-binding domain
E2F_CC-MBaa 206–299UCSCE2F transcription factor CC-MB domain

Gene Aliases

HGNC Name

E2F transcription factor 1

HGNC Previous Symbol

RBBP3

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_005225.3
p.K161R
c.482A>G
Surrounding Variants
1 paper
NM_005225.3
p.K164*
c.490A>T
2 papers
NM_005225.3
p.K164R
c.491A>G
1 paper
NM_005225.3
p.R165P
c.494G>C
1 paper
NM_005225.3
p.R165Q
c.494G>A
1 paper
NM_005225.3
p.A156A
c.468T>G
7 papers
NM_005225.3
p.R166H
c.497G>A
7 papers
NM_005225.3
p.I167V
c.499A>G
1 paper
NM_005225.3
p.L153V
c.457C>G
1 paper
NM_005225.3
p.I170N
c.509T>A
1 paper
NM_005225.3
p.D152H
c.454G>C
1 paper
NM_005225.3
p.V150A
c.449T>C
1 paper
NM_005225.3
p.V173F
c.517G>T
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."