Varaico: Literature-Extracted Genetic Variants

EPHB2

2,780 papers

RefSeq Summary

This gene encodes a member of the Eph receptor family of receptor tyrosine kinase transmembrane glycoproteins. These receptors are composed of an N-terminal glycosylated ligand-binding domain, a trans...

Pfam Domains

Ephrin_lbdaa 21–197UCSCEphrin receptor ligand binding domain

Ephrin_CRDaa 198–256UCSCEphrin cysteine rich domain

Ephrin_rec_likeaa 260–304UCSCTyrosine-protein kinase ephrin type A/B receptor-like

fn3aa 326–427UCSCFibronectin type III domain

fn3aa 434–526UCSCFibronectin type III domain

EphA2_TMaa 544–618UCSCEphrin type-A receptor 2 transmembrane domain

Gene Aliases

HGNC Name

EPH receptor B2

HGNC Previous Symbols

DRT; ERK; EPHT3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_017449.5

p.L655H

c.1964T>A

Surrounding Variants

1 paper

NM_017449.5

p.K656E

c.1966A>G

2 papers

NM_017449.5

p.K653R

c.1958A>G

1 paper

NM_017449.5

p.K653*

c.1957A>T

1 paper

NM_017449.5

p.G658S

c.1972G>A

1 paper

NM_017449.5

p.G658R

c.1972G>C

1 paper

NM_017449.5

p.G658C

c.1972G>T

2 papers

NM_017449.5

p.T660M

c.1979C>T

1 paper

NM_017449.5

p.V650A

c.1949T>C

3 papers

NM_017449.5

p.K662R

c.1985A>G

1 paper

NM_017449.5

p.I648insFs

c.1943dupT

2 papers

NM_017449.5

p.R664H

c.1991G>A

2 papers

NM_017449.5

p.R665W

c.1993C>T