Varaico: Literature-Extracted Genetic Variants

FGB

368 papers

RefSeq Summary

The protein encoded by this gene is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is c...

Pfam Domains

Fib_alphaaa 91–234UCSCFibrinogen alpha/beta chain family

Fibrinogen_Caa 237–487UCSCFibrinogen beta and gamma chains, C-terminal globular domain

Gene Aliases

HGNC Name

fibrinogen beta chain

HGNC Previous Name

fibrinogen, B beta polypeptide

Papers

RefSeq ID

Protein change

DNA change

1–12 of 388 variants

25 papers

NM_005141.5

p.R285H

c.854G>A

22 papers

NM_005141.5

p.R478K

c.1433G>A

14 papers

NM_005141.5

p.R47*

c.139C>T

14 papers

NM_005141.5

p.W467*

c.1400G>A

14 papers

NM_005141.5

p.W467*

c.1401G>A

12 papers

NM_005141.5

p.P265L

c.794C>T

11 papers

NM_005141.5

p.W415Splc

c.1244+1G>T

11 papers

NM_005141.5

p.G444S

c.1330G>A

10 papers

NM_005141.5

p.K152R

c.455A>G

10 papers

NM_005141.5

p.G430D

c.1289G>A

9 papers

NM_005141.5

p.E38_G39Splc

c.115-600A>G

9 papers

NM_005141.5

p.R44C

c.130C>T