Varaico: Literature-Extracted Genetic Variants

FGFR2

2,640 papers

RefSeq Summary

The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family member...

Pfam Domains

Ig_3aa 38–110UCSCImmunoglobulin domain

I-setaa 72–159UCSCImmunoglobulin I-set domain

Ig_3aa 167–257UCSCImmunoglobulin domain

PK_Tyr_Ser-Thraa 392–668UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

fibroblast growth factor receptor 2

HGNC Previous Symbols

KGFR; BEK; CFD1; JWS

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000141.5

p.K641K

c.1923A>G

Surrounding Variants

7 papers

NM_000141.5

p.K641N

c.1923A>T

NM_022970.4

p.K642N

c.1926A>T

7 papers

NM_000141.5

p.K641N

c.1923A>C

NM_022970.4

p.K642N

c.1926A>C

2 papers

NM_000141.5

p.K641I

c.1922A>T

1 paper

NM_000141.5

p.I642L

c.1924A>T

47 papers

NM_000141.5

p.K641R

c.1922A>G

NM_022970.4

p.K642R

c.1925A>G

8 papers

NM_000141.5

p.I642V

c.1924A>G

1 paper

NM_000141.5

p.I642L

c.1924A>C

1 paper

NM_000141.5

p.K641T

c.1922A>C

1 paper

NM_000141.5

p.M640del1

c.1918_1919delCAT

1 paper

NM_000141.5

p.I642R

c.1925T>G

1 paper

NM_000141.5

p.I642T

c.1925T>C

2 papers

NM_000141.5

p.I642K

c.1925T>A