Varaico: Literature-Extracted Genetic Variants

FLT3

2,401 papers

RefSeq Summary

This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, whic...

Pfam Domains

igaa 258–343UCSCImmunoglobulin domain

PK_Tyr_Ser-Thraa 610–943UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

fms related receptor tyrosine kinase 3

HGNC Alias Symbols

FLK2; CD135

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_004119.3

p.F594_R595ins10

c.1780_1784ins30

Surrounding Variants

1 paper

NM_004119.3

p.F594ins16

c.1780_1781ins48

1 paper

NM_004119.3

p.M578_D593ins5

c.1732_1779dup48

1 paper

NM_004119.3

p.F594insFs

c.1780_1781insGG

1 paper

NM_004119.3

p.F594ins9

c.1780_1781ins27

2 papers

NM_004119.3

p.F594_R595ins11

c.1780_1784ins33

1 paper

NM_004119.3

p.F594_R595ins12

c.1780_1784ins36

1 paper

NM_004119.3

p.F594_R595ins14

c.1780_1784ins42

1 paper

NM_004119.3

p.F594ins2

c.1780_1781ins6

7 papers

NM_004119.3

p.F594V

c.1780T>G

35 papers

NM_004119.3

p.F594L

c.1780T>C

9 papers

NM_004119.3

p.F594I

c.1780T>A

3 papers

NM_004119.3

p.D593del1

c.1777_1779delATC