Varaico: Literature-Extracted Genetic Variants

FLT3

2,401 papers

RefSeq Summary

This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, whic...

Pfam Domains

igaa 258–343UCSCImmunoglobulin domain

PK_Tyr_Ser-Thraa 610–943UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

fms related receptor tyrosine kinase 3

HGNC Alias Symbols

FLK2; CD135

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

19 papers

NM_004119.3

p.L4F

c.12G>C

Surrounding Variants

1 paper

NM_004119.3

p.L4insFs

c.10dupT

11 papers

NM_004119.3

p.L4L

c.12G>A

4 papers

NM_004119.3

p.A5P

c.13G>C

2 papers

NM_004119.3

p.A5T

c.13G>A

1 paper

NM_004119.3

p.L4insFs

c.12dupG

2 papers

NM_004119.3

p.A5E

c.14C>A

1 paper

NM_004119.3

p.A3A

c.9G>T

1 paper

NM_004119.3

p.A3A

c.9G>A

1 paper

NM_004119.3

p.M1_P2del0

c.1_6del6

1 paper

NM_004119.3

p.R6delFs

c.16delG

1 paper

NM_004119.3

p.P2_A5del4

c.4_14del12

1 paper

NM_004119.3

p.P2insFs

c.4dupC