Varaico: Literature-Extracted Genetic Variants

FOXO3

295 papers

RefSeq Summary

This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of gen...

Pfam Domains

Forkheadaa 157–245UCSCForkhead domain

FOXO_KIX_bdgaa 432–511UCSCKIX-binding domain of forkhead box O, CR2

FOXO-TADaa 604–645UCSCTransactivation domain of FOXO protein family

Gene Aliases

HGNC Name

forkhead box O3

HGNC Previous Symbols

FKHRL1; FOXO3A

Papers

RefSeq ID

Protein change

DNA change

1–12 of 241 variants

14 papers

NM_001455.4

p.G381insFs

c.1141dupG

13 papers

NM_001455.4

p.A341T

c.1021G>A

9 papers

NM_001455.4

p.S253A

c.757T>G

9 papers

NM_001455.4

p.S315A

c.943T>G

8 papers

NM_001455.4

p.A140V

c.419C>T

8 papers

NM_001455.4

p.L382fs

c.1144_1145fs

7 papers

NM_001455.4

p.L11H

c.32T>A

7 papers

NM_001455.4

p.T32A

c.94A>G

7 papers

NM_001455.4

p.D380fs

c.1138_1139fs

7 papers

NM_001455.4

p.R506H

c.1517G>A

6 papers

NM_001455.4

p.D62N

c.184G>A

6 papers

NM_001455.4

p.R189H

c.566G>A