Varaico: Literature-Extracted Genetic Variants

Gene:GCGR
Variant:p.W87C

GCGR

217 papers

RefSeq Summary

The protein encoded by this gene is a glucagon receptor that is important in controlling blood glucose levels. Defects in this gene are a cause of non-insulin-dependent diabetes mellitus (NIDDM).[prov...

Pfam Domains

HRMaa 55–124UCSCHormone receptor domain
7tm_2aa 138–396UCSC7 transmembrane receptor (Secretin family)

Gene Aliases

HGNC Name

glucagon receptor

HGNC Alias Symbol

GGR

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000160.5
p.W87C
c.261G>T
Surrounding Variants
1 paper
NM_000160.5
p.W87C
c.261G>C
1 paper
NM_000160.5
p.H88N
c.262C>A
18 papers
NM_000160.5
p.P86S
c.256C>T
1 paper
NM_000160.5
p.H89Q
c.267C>A
1 paper
NM_000160.5
p.H89Q
c.267C>G
1 paper
NM_000160.5
p.Y84*
c.252C>A
1 paper
NM_000160.5
p.Y84*
c.252C>G
1 paper
NM_000160.5
p.V91M
c.271G>A
1 paper
NM_000160.5
p.W83*
c.249G>A
1 paper
NM_000160.5
p.W83C
c.249G>C
1 paper
NM_000160.5
p.W83C
c.249G>T
1 paper
NM_000160.5
p.W83*
c.248G>A
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."