Varaico: Literature-Extracted Genetic Variants

GRIK3

180 papers

RefSeq Summary

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to t...

Pfam Domains

ANF_receptoraa 55–400UCSCReceptor family ligand binding region

Lig_chan-Glu_bdaa 434–548UCSCLigated ion channel L-glutamate- and glycine-binding site

Lig_chanaa 562–832UCSCLigand-gated ion channel

Gene Aliases

HGNC Name

glutamate ionotropic receptor kainate type subunit 3

HGNC Alias Symbols

GluK3; GLUR7

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_000831.4

p.R357H

c.1070G>A

Surrounding Variants

1 paper

NM_000831.4

p.R357C

c.1069C>T

4 papers

NM_000831.4

p.G360S

c.1078G>A

3 papers

NM_000831.4

p.R361H

c.1082G>A

1 paper

NM_000831.4

p.R361R

c.1083C>T

1 paper

NM_000831.4

p.K367N

c.1101G>T

1 paper

NM_000831.4

p.K367N

c.1101G>C

1 paper

NM_000831.4

p.V335L

c.1003G>T

1 paper

NM_000831.4

p.V335L

c.1003G>C

2 papers

NM_000831.4

p.V330I

c.988G>A

1 paper

NM_000831.4

p.D328N

c.982G>A

1 paper

NM_000831.4

p.E368_A369Splc

c.1104+147C>T

31 papers

NM_000831.4

p.S310A

c.928T>G