Varaico: Literature-Extracted Genetic Variants

GRK2

235 papers

RefSeq Summary

This gene encodes a member of the G protein-coupled receptor kinase family of proteins. The encoded protein phosphorylates the beta-adrenergic receptor as well as a wide range of other substrates incl...

Pfam Domains

RGSaa 54–174UCSCRegulator of G protein signaling domain

Pkinaseaa 191–453UCSCProtein kinase domain

PHaa 559–652UCSCPH domain

Gene Aliases

HGNC Name

G protein-coupled receptor kinase 2

HGNC Previous Symbol

ADRBK1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001619.5

p.K663E

c.1987A>G

Surrounding Variants

1 paper

NM_001619.5

p.K663Q

c.1987A>C

1 paper

NM_001619.5

p.K665Q

c.1993A>C

1 paper

NM_001619.5

p.K665E

c.1993A>G

1 paper

NM_001619.5

p.R660Q

c.1979G>A

1 paper

NM_001619.5

p.N666S

c.1997A>G

1 paper

NM_001619.5

p.K667E

c.1999A>G

5 papers

NM_001619.5

p.S670A

c.2008T>G

1 paper

NM_001619.5

p.E653Q

c.1957G>C

1 paper

NM_001619.5

p.R648C

c.1942C>T

1 paper

NM_001619.5

p.L647V

c.1939C>G

1 paper

NM_001619.5

p.E646Q

c.1936G>C

1 paper

NM_001619.5

p.K645Q

c.1933A>C