Varaico: Literature-Extracted Genetic Variants

Gene:GRK4
Variant:p.K175N

GRK4

160 papers

RefSeq Summary

This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms ...

Pfam Domains

RGSaa 52–171UCSCRegulator of G protein signaling domain
Pkinaseaa 187–449UCSCProtein kinase domain

Gene Aliases

HGNC Name

G protein-coupled receptor kinase 4

HGNC Previous Symbol

GPRK2L

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_182982.3
p.K175N
c.525A>T
Surrounding Variants
1 paper
NM_182982.3
p.K175N
c.525A>C
1 paper
NM_182982.3
p.Q173*
c.517C>T
1 paper
NM_182982.3
p.L154V
c.460C>G
4 papers
NM_182982.3
p.A150S
c.448G>T
1 paper
NM_182982.3
p.T183R
c.548C>G
2 papers
NM_182982.3
p.R191K
c.572G>A
1 paper
NM_182982.3
p.V192A
c.575T>C
1 paper
NM_182982.3
p.R148Splc
c.443+8G>C
1 paper
NM_182982.3
p.F143Y
c.428T>A
53 papers
NM_182982.3
p.A142V
c.425C>T
1 paper
NM_182982.3
p.A142fs
c.424_425fs
1 paper
NM_182982.3
p.S139C
c.416C>G
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