Varaico: Literature-Extracted Genetic Variants

GRM3

337 papers

RefSeq Summary

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in mo...

Pfam Domains

ANF_receptoraa 67–474UCSCReceptor family ligand binding region

NCD3Gaa 504–555UCSCNine Cysteines Domain of family 3 GPCR

7tm_3aa 570–822UCSC7 transmembrane sweet-taste receptor of 3 GCPR

Gene Aliases

HGNC Name

glutamate metabotropic receptor 3

HGNC Alias Symbols

GPRC1C; mGlu3; MGLUR3

Papers

RefSeq ID

Protein change

DNA change

1–12 of 433 variants

9 papers

NM_000840.3

p.E870K

c.2608G>A

8 papers

NM_000840.3

p.G18E

c.53G>A

7 papers

NM_000840.3

p.G475D

c.1424G>A

6 papers

NM_000840.3

p.S610L

c.1829C>T

5 papers

NM_000840.3

p.R59Q

c.176G>A

5 papers

NM_000840.3

p.R352W

c.1054C>T

5 papers

NM_000840.3

p.M518I

c.1554G>A

5 papers

NM_000840.3

p.M518I

c.1554G>C

5 papers

NM_000840.3

p.M518I

c.1554G>T

5 papers

NM_000840.3

p.E767K

c.2299G>A

5 papers

NM_000840.3

p.G848E

c.2543G>A

4 papers

NM_000840.3

p.V372I

c.1114G>A