Varaico: Literature-Extracted Genetic Variants

GRM3

337 papers

RefSeq Summary

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in mo...

Pfam Domains

ANF_receptoraa 67–474UCSCReceptor family ligand binding region

NCD3Gaa 504–555UCSCNine Cysteines Domain of family 3 GPCR

7tm_3aa 570–822UCSC7 transmembrane sweet-taste receptor of 3 GCPR

Gene Aliases

HGNC Name

glutamate metabotropic receptor 3

HGNC Alias Symbols

GPRC1C; mGlu3; MGLUR3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000840.3

p.D873N

c.2617G>A

Surrounding Variants

1 paper

NM_000840.3

p.V871F

c.2611G>T

9 papers

NM_000840.3

p.E870K

c.2608G>A

4 papers

NM_000840.3

p.R869Q

c.2606G>A

1 paper

NM_000840.3

p.R869W

c.2605C>T

1 paper

NM_000840.3

p.G868G

c.2604G>A

1 paper

NM_000840.3

p.T864A

c.2590A>G

1 paper

NM_000840.3

p.T860A

c.2578A>G

1 paper

NM_000840.3

p.S857A

c.2569T>G