Varaico: Literature-Extracted Genetic Variants

Gene:HDAC1
Variant:p.E426A

HDAC1

495 papers

RefSeq Summary

Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone dea...

Pfam Domains

Hist_deacetylaa 28–319UCSCHistone deacetylase domain

Gene Aliases

HGNC Name

histone deacetylase 1

HGNC Previous Symbol

RPD3L1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
2 papers
NM_004964.3
p.E426A
c.1277A>C
Surrounding Variants
1 paper
NM_004964.3
p.E425A
c.1274A>C
1 paper
NM_004964.3
p.E425Q
c.1273G>C
1 paper
NM_004964.3
p.E424A
c.1271A>C
1 paper
NM_004964.3
p.G430delFs
c.1289delG
4 papers
NM_004964.3
p.S423A
c.1267T>G
1 paper
NM_004964.3
p.G430fs
c.1288_1289fs
3 papers
NM_004964.3
p.S421A
c.1261T>G
2 papers
NM_004964.3
p.K432Q
c.1294A>C
1 paper
NM_004964.3
p.F420L
c.1260C>A
1 paper
NM_004964.3
p.F420L
c.1260C>G
1 paper
NM_004964.3
p.K432R
c.1295A>G
1 paper
NM_004964.3
p.K432K
c.1296G>A
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."