Varaico: Literature-Extracted Genetic Variants

HDAC4

311 papers

RefSeq Summary

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription f...

Pfam Domains

HDAC4_Glnaa 62–152UCSCGlutamine rich N terminal domain of histone deacetylase 4

Hist_deacetylaa 675–992UCSCHistone deacetylase domain

Gene Aliases

HGNC Name

histone deacetylase 4

HGNC Previous Symbol

BDMR

Papers

RefSeq ID

Protein change

DNA change

1–12 of 235 variants

8 papers

NM_001378414.1

p.S246A

c.736T>G

7 papers

NM_001378414.1

p.E262D

c.786A>T

4 papers

NM_001378414.1

p.A185V

c.554C>T

4 papers

NM_001378414.1

p.G220R

c.658G>C

4 papers

NM_001378414.1

p.G220R

c.658G>A

4 papers

NM_001378414.1

p.A800insFs

c.2399_2400insC

3 papers

NM_001378414.1

p.T223T

c.669C>A

3 papers

NM_001378414.1

p.G901delFs

c.2703delG

2 papers

NM_001378414.1

p.M1insFs

c.2dupT

2 papers

NM_001378414.1

p.G12V

c.35G>T

2 papers

NM_001378414.1

p.T31T

c.93G>A

2 papers

NM_001378414.1

p.R52H

c.155G>A