Varaico: Literature-Extracted Genetic Variants

Gene:HTR1B
Variant:p.F124C

HTR1B

361 papers

RefSeq Summary

The protein encoded by this intronless gene is a G-protein coupled receptor for serotonin (5-hydroxytryptamine). Ligand binding activates second messengers that inhibit the activity of adenylate cycla...

Pfam Domains

7tm_1aa 66–369UCSC7 transmembrane receptor (rhodopsin family)

Gene Aliases

HGNC Name

5-hydroxytryptamine receptor 1B

HGNC Alias Symbols

S12; 5-HT1B; HTR1D2; 5-HT1DB

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
26 papers
NM_000863.3
p.F124C
c.371T>G
Surrounding Variants
1 paper
NM_000863.3
p.F124V
c.370T>G
1 paper
NM_000863.3
p.S127S
c.381G>T
1 paper
NM_000863.3
p.I130I
c.390C>T
1 paper
NM_000863.3
p.R114R
c.342C>A
1 paper
NM_000863.3
p.T107I
c.320C>T
1 paper
NM_000863.3
p.I143L
c.427A>C
1 paper
NM_000863.3
p.I105fs
c.313_314fs
1 paper
NM_000863.3
p.M103I
c.309G>T
1 paper
NM_000863.3
p.M103I
c.309G>C
1 paper
NM_000863.3
p.M103I
c.309G>A
1 paper
NM_000863.3
p.R147R
c.441C>A
1 paper
NM_000863.3
p.V98L
c.292G>T
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