Varaico: Literature-Extracted Genetic Variants

Gene:IDH2
Variant:p.W132*

IDH2

2,456 papers

RefSeq Summary

Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor...

Pfam Domains

Iso_dhaa 45–441UCSCIsocitrate/isopropylmalate dehydrogenase

Gene Aliases

HGNC Name

isocitrate dehydrogenase (NADP(+)) 2

HGNC Alias Symbol

IDH-2

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
29 papers
NM_002168.4
p.W132*
c.395G>A
Surrounding Variants
9 papers
NM_002168.4
p.W132L
c.395G>T
2 papers
NM_002168.4
p.W132S
c.395G>C
2 papers
NM_002168.4
p.W132delins
c.394_395delinsGT
1 paper
NM_002168.4
p.W132delins
c.394_395delinsAT
1 paper
NM_002168.4
p.M131_W132delins
c.392_396delinsTCCTG
1 paper
NM_002168.4
p.W132*
c.396G>A
2 papers
NM_002168.4
p.M131I
c.393G>T
2 papers
NM_002168.4
p.M131I
c.393G>C
2 papers
NM_002168.4
p.M131I
c.393G>A
1 paper
NM_002168.4
p.K130del1
c.388_389delCTT
2 papers
NM_002168.4
p.K133R
c.398A>G
2 papers
NM_002168.4
p.K130M
c.389A>T
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."