Varaico: Literature-Extracted Genetic Variants

Gene:IL4R
Variant:p.T487M

IL4R

559 papers

RefSeq Summary

This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can ...

Pfam Domains

IL4Ra_Naa 28–121UCSCInterleukin-4 receptor alpha chain, N-terminal

Gene Aliases

HGNC Name

interleukin 4 receptor

HGNC Alias Symbol

CD124

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000418.4
p.T487M
c.1460C>T
Surrounding Variants
1 paper
NM_000418.4
p.P488P
c.1464C>G
2 papers
NM_000418.4
p.L489P
c.1466T>C
2 papers
NM_000418.4
p.A492T
c.1474G>A
2 papers
NM_000418.4
p.A492V
c.1475C>T
1 paper
NM_000418.4
p.N494N
c.1482C>T
2 papers
NM_000418.4
p.Y497F
c.1490A>T
1 paper
NM_000418.4
p.P475L
c.1424C>T
2 papers
NM_000418.4
p.A473S
c.1417G>T
1 paper
NM_000418.4
p.N502S
c.1505A>G
1 paper
NM_000418.4
p.P472A
c.1414C>G
88 papers
NM_000418.4
p.S503P
c.1507T>C
1 paper
NM_000418.4
p.P472_T483del12
c.1414_1448del36
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."