Varaico: Literature-Extracted Genetic Variants

Gene:IL4R
Variant:p.P515S

IL4R

559 papers

RefSeq Summary

This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can ...

Pfam Domains

IL4Ra_Naa 28–121UCSCInterleukin-4 receptor alpha chain, N-terminal

Gene Aliases

HGNC Name

interleukin 4 receptor

HGNC Alias Symbol

CD124

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
2 papers
NM_000418.4
p.P515S
c.1543C>T
Surrounding Variants
1 paper
NM_000418.4
p.H522D
c.1564C>G
88 papers
NM_000418.4
p.S503P
c.1507T>C
1 paper
NM_000418.4
p.N502S
c.1505A>G
1 paper
NM_000418.4
p.M530I
c.1590G>T
2 papers
NM_000418.4
p.Y497F
c.1490A>T
1 paper
NM_000418.4
p.N494N
c.1482C>T
2 papers
NM_000418.4
p.A492V
c.1475C>T
2 papers
NM_000418.4
p.A492T
c.1474G>A
1 paper
NM_000418.4
p.P539L
c.1616C>T
2 papers
NM_000418.4
p.L489P
c.1466T>C
1 paper
NM_000418.4
p.T541_V542insFs
c.1623_1624insT
1 paper
NM_000418.4
p.P488P
c.1464C>G
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