Varaico: Literature-Extracted Genetic Variants

Gene:IRAK1
Variant:p.T54A

IRAK1

294 papers

RefSeq Summary

This gene encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. This gene...

Pfam Domains

Deathaa 27–103UCSCDeath domain
Pkinaseaa 212–517UCSCProtein kinase domain

Gene Aliases

HGNC Name

interleukin 1 receptor associated kinase 1

HGNC Alias Symbol

pelle

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_001569.4
p.T54A
c.160A>G
Surrounding Variants
1 paper
NM_001569.4
p.Q53Q
c.159G>A
1 paper
NM_001569.4
p.E55*
c.163G>T
1 paper
NM_001569.4
p.R51C
c.151C>T
2 papers
NM_001569.4
p.V50A
c.149T>C
2 papers
NM_001569.4
p.L58L
c.174G>C
1 paper
NM_001569.4
p.A47G
c.140C>G
1 paper
NM_001569.4
p.R61C
c.181C>T
1 paper
NM_001569.4
p.A46S
c.136G>T
1 paper
NM_001569.4
p.R65C
c.193C>T
4 papers
NM_001569.4
p.T66A
c.196A>G
1 paper
NM_001569.4
p.A67D
c.200C>A
3 papers
NM_001569.4
p.L70Q
c.209T>A
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."