Varaico: Literature-Extracted Genetic Variants

IRF6

504 papers

RefSeq Summary

This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C...

Pfam Domains

IRFaa 9–114UCSCInterferon regulatory factor transcription factor

IRF-3aa 223–407UCSCInterferon-regulatory factor 3

Gene Aliases

HGNC Name

interferon regulatory factor 6

HGNC Previous Symbols

VWS; LPS

Papers

RefSeq ID

Protein change

DNA change

1–12 of 722 variants

105 papers

NM_006147.4

p.V274I

c.820G>A

61 papers

NM_006147.4

p.R84C

c.250C>T

24 papers

NM_006147.4

p.R412*

c.1234C>T

23 papers

NM_006147.4

p.R84H

c.251G>A

20 papers

NM_006147.4

p.R250Q

c.749G>A

18 papers

NM_006147.4

p.R9W

c.25C>T

18 papers

NM_006147.4

p.R400W

c.1198C>T

14 papers

NM_006147.4

p.R6C

c.16C>T

13 papers

NM_006147.4

p.P76S

c.226C>T

12 papers

NM_006147.4

p.R45Q

c.134G>A

12 papers

NM_006147.4

p.D354N

c.1060G>A

12 papers

NM_006147.4

p.R400Q

c.1199G>A