Varaico: Literature-Extracted Genetic Variants

ITGAM

620 papers

RefSeq Summary

This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with ...

Pfam Domains

VWAaa 150–327UCSCvon Willebrand factor type A domain

FG-GAPaa 457–494UCSCFG-GAP repeat

FG-GAPaa 520–555UCSCFG-GAP repeat

Integrin_A_Ig_1aa 614–769UCSCIntegrin alpha Ig-like domain 1

Integrin_A_Ig_2aa 770–921UCSCIntegrin alpha Ig-like domain 2

ITGAX-like_Ig_3aa 922–1101UCSCIntegrin alpha-X-like, Ig-like domain 3

Gene Aliases

HGNC Name

integrin subunit alpha M

HGNC Previous Symbols

CR3A; CD11B

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000632.4

p.T1093M

c.3278C>T

Surrounding Variants

1 paper

NM_000632.4

p.A1126V

c.3377C>T

1 paper

NM_000632.4

p.S1142N

c.3425G>A

2 papers

NM_000632.4

p.G1145S

c.3433G>A

16 papers

NM_000632.4

p.P1146S

c.3436C>T

1 paper

NM_000632.4

p.P1147S

c.3439C>T

1 paper

NM_000632.4

p.V1078M

c.3232G>A

2 papers

NM_000632.4

p.E1071D

c.3213G>C

2 papers

NM_000632.4

p.E1071D

c.3213G>T

1 paper

NM_000632.4

p.Y1056H

c.3166T>C

1 paper

NM_000632.4

p.N1050Y

c.3148A>T

1 paper

NM_000632.4

p.Q1031H

c.3093G>T

1 paper

NM_000632.4

p.A1025V

c.3074C>T