Varaico: Literature-Extracted Genetic Variants

KLF11

127 papers

RefSeq Summary

The protein encoded by this gene is a zinc finger transcription factor that binds to SP1-like sequences in epsilon- and gamma-globin gene promoters. This binding inhibits cell growth and causes apopto...

Pfam Domains

zf-C2H2aa 394–418UCSCZinc finger, C2H2 type

zf-C2H2aa 424–448UCSCZinc finger, C2H2 type

zf-C2H2aa 454–476UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

KLF transcription factor 11

HGNC Previous Symbol

TIEG2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003597.5

p.M45L

c.133A>C

Surrounding Variants

1 paper

NM_003597.5

p.M45L

c.133A>T

2 papers

NM_003597.5

p.E49K

c.145G>A

1 paper

NM_003597.5

p.E49*

c.145G>T

1 paper

NM_003597.5

p.E33_R34del2

c.97_101del6

1 paper

NM_003597.5

p.R60I

c.179G>T

3 papers

NM_003597.5

p.R29Q

c.86G>A

1 paper

NM_003597.5

p.R29W

c.85C>T

1 paper

NM_003597.5

p.Q62*

c.184C>T

20 papers

NM_003597.5

p.Q62R

c.185A>G

1 paper

NM_003597.5

p.E26K

c.76G>A

1 paper

NM_003597.5

p.I69T

c.206T>C

1 paper

NM_003597.5

p.R70fs

c.208_209fs